disease:A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein.,similarity:Contains 1 YEATS domain.,subunit:Interacts with BCOR. Interacts with CBX8.,
Nucleus . Chromosome . Colocalizes with acylated histone H3 (PubMed:25417107, PubMed:27105114). Colocalizes with histone H3 crotonylated at 'Lys-18' (H3K18cr) (PubMed:27105114). .
Enriched in undifferentiated hematopoietic stem cells in fetal liver, cord blood and bone marrow.
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