function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.,
Cul2-RING ubiquitin ligase complex,
Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.