disease:Rearrangements occur in breast and ovarian cancers which involve multiple exons and disrupt the coding region.,domain:A conserved motif [AVN[ED]CD] within the disintegrin-like domain could be involved in the binding to the integrin receptor.,function:Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Expressed predominantly in brain. Slightly detected or not at all in other tissues.,
Membrane; Single-pass type I membrane protein.
Expressed predominantly in brain. Slightly detected or not at all in other tissues.
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