similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 1 WAP domain.,tissue specificity:Expressed in epididymis and testis.,tissue specificity:Ubiquitously expressed, but the highest levels are found in epididymis, testis and trachea.,
[Isoform 1]: Secreted. Cell surface. Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells.
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