function:Act as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.,induction:By GATA-1 during erythroid maturation.,similarity:Belongs to the AHSP family.,subunit:Monomer. Forms an heterodimer with free alpha-hemoglobin. Does not bind beta-hemoglobin nor alpha(2)beta(2) hemoglobin A.,tissue specificity:Expressed in blood and bone marrow.,
Cytoplasm .
Expressed in blood and bone marrow.
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