HBG1 rabbit pAb

developmental stage:Expressed until four or five weeks after birth.,disease:Some gamma variants can cause severe jaundice and cyanosis in premature and new born babies.,function:Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.,online information:Human hemoglobin variants and thalassemias,PTM:Acetylation of Gly-2 converts Hb F to the minor Hb F1.,similarity:Belongs to the globin family.,subunit:Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F). In the case of deletions affecting one or more of the alpha chains the excess gamma chains form homotetramers that exhibit neither Bohr effect nor heme-heme cooperativity (hemoglobin Bart's).,tissue specificity:Red blood cells.,