catalytic activity:Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2).,cofactor:Pyridoxal phosphate.,miscellaneous:There are two delta-ALA synthetase in vertebrates: an erythroid- specific form and one (housekeeping) which is expressed in all tissues.,pathway:Porphyrin metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.,similarity:Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
Mitochondrion inner membrane ; Peripheral membrane protein . Localizes to the matrix side of the mitochondrion inner membrane. .
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