UPP2 rabbit pAb

catalytic activity:Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,function:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.,similarity:Belongs to the PNP/UDP phosphorylase family.,tissue specificity:Predominantly expressed in kidney.,