function:Probably plays a role in the regulation of cell adhesion and cytoskeleton organization.,similarity:Belongs to the parvin family.,similarity:Contains 2 CH (calponin-homology) domains.,subcellular location:Constituent of focal adhesions.,subunit:Interacts with TGFB1I1 (By similarity). Interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. Interacts with CDGAP.,tissue specificity:Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.,
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line . Constituent of focal adhesions. Associates with the actin cytoskeleton.
Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver.
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