B3GL1 rabbit pAb

catalytic activity:UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.,cofactor:Magnesium.,function:Transfers N-acetylgalactosamine onto globotriaosylceramide.,online information:Beta-1,3-galactosyltransferase 3,online information:Blood group antigen gene mutation database,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,polymorphism:Different combinations or absence of the P blood group system antigens define 5 different phenotypes: P1, P2, P1(k), P2(k), and P. Genetic variation in B3GALT3 determines the P1(k) and P2(k) phenotype, which is rare and lack the capability to synthesize P antigen identified as globoside.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:Higher expression in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach. No expression in skeletal muscle.,