catalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,function:Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.,pathway:Lipid metabolism; glycerolipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.,
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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