domain:Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.,function:Belongs to the 26S multisubunit protease, which is required for ubiquitin-dependent proteolysis. Does not bind ubiquitin polymers.,similarity:Belongs to the proteasome subunit S5B family.,subunit:26S protease is composed of a multicatalytic protease (proteasome) and a regulatory ATPase complex. Both are multisubunit structures that associate in the presence of ATP to form the protease. Subunit S5B is part of the regulatory complex.,
proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle, base subcomplex,proteasome accessory complex,
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