STRAB rabbit pAb

caution:Ser-184 is present instead of the conserved Asp which is expected to be an active site residue.,domain:The protein kinase domain is predicted to be catalytically inactive.,function:Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with BIRC4/XIAP. These two proteins are likely to coexist in a complex with TAK1, TRAF6, TAB1 and TAB2.,tissue specificity:Highly expressed in heart, skeletal muscle, testis, liver and colon.,