catalytic activity:ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.,caution:The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.,function:Synthesizes selenophosphate from selenide and ATP.,similarity:Belongs to the selenophosphate synthetase 1 family. Class II subfamily.,
[Isoform 1]: Cell membrane ; Peripheral membrane protein . Nucleus membrane ; Peripheral membrane protein .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm .
[Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 3]: Gradually expressed during the cell cycle until S phase and then decreases.
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