UBIP1 rabbit pAb

function:Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.,induction:Induced by HIV-1 infection of lymphocytes.,similarity:Belongs to the grh/CP2 family. CP2 subfamily.,subunit:Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.,tissue specificity:Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.,