function:May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.,similarity:Contains 1 thioredoxin domain.,subcellular location:Predominantly found in the endoplasmic reticulum.,tissue specificity:Ubiquitous. Highly expressed in kidney, liver, placenta and lung.,
Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Predominantly found in the endoplasmic reticulum. .
Ubiquitous. Highly expressed in kidney, liver, placenta and lung.
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