MTMR5 rabbit pAb

function:Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.,similarity:Contains 1 dDENN domain.,similarity:Contains 1 DENN domain.,similarity:Contains 1 GRAM domain.,similarity:Contains 1 myotubularin phosphatase domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 uDENN domain.,subunit:Interacts with the SET domain of MLL/HRX. Interacts with SUV39H1.,