SSX2 rabbit pAb

Catalog Number：

RA07394
Size：

40μL 100μL 200μL
Price：

960 / 2300 / 3780 RMB(含税报价)
Form：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reactivity：

Human ; Mouse ; Rat
Application：

WB

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功能

细胞定位

组织表达

disease:A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,function:Could act as a modulator of transcription.,similarity:Belongs to the SSX family.,similarity:Contains 1 KRAB-related domain.,subunit:Interacts via its N-terminal region with RAB3IP and SSX2IP.,tissue specificity:Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.,

Nucleus.

Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.