cofactor:Binds 1 zinc ion per subunit .,function:Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.,similarity:Belongs to the aldolase class II family. APIP subfamily.,subunit:Interacts with APAF1.,tissue specificity:Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.,
Cytoplasm .
Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.
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