Cell membrane, sarcolemma ; Single-pass type I membrane protein . Apical cell membrane ; Single-pass type I membrane protein . Membrane, caveola . Cell membrane, sarcolemma, T-tubule . Detected in the apical cell membrane in brain. In myocytes, localizes to sarcolemma, t-tubules and intercalated disks. .
Highest expression in skeletal muscle and heart. Moderate levels in brain, placenta, lung, liver, pancreas, uterus, bladder, prostate, small intestine and colon with mucosal lining. Very low levels in kidney, colon and small intestine without mucosa, prostate without endothelial lining, spleen, and testis.
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