transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter,cell cycle, cell proliferation, regulation of transcription, regulation of RNA metabolic process,
Nucleus . Cytoplasm . Shuttles between the cytoplasm and nucleus and translocates into the nuclear compartment upon heterodimerization with E2F1. .
Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.