Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Also found in myotendinous junctions and in the postsynaptic membrane of neuromuscular junctions. .
Isoform 1 is expressed exclusively in heart and skeletal muscle. Isoform 2 is expressed in heart, skeletal muscle, thymus, prostate, testis, ovary, small intestine, colon and spleen.