Cytoplasm.; [Isoform 1]: Cell membrane. Cytoplasmic vesicle. Localized to the plasma membrane and intracellular vesicles, including late endosomal vesicles.; [Isoform 2]: Cytoplasm . May be cytoplasmic and is not localized to membranes.
Predominantly expressed in immune system, with highest levels in peripheral blood leukocytes. Expressed in spleen, thymus and lymph nodes. Expressed in T-cells as well as in monocytes, and at low level in B-cells. Also detected in placenta, prostate, skin, retina and colon.