Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Cell projection, cilium, flagellum . Colocalizes with ENTR1 and gamma-tubulin at the basal body of primary cilia. Colocalizes with ENTR1 and pericentrin at the centrosome. .
Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
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