Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cleavage furrow . Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
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