Required for proper contractility of visceral smooth muscle cells . Mediates nucleation of actin filaments.
Cytoplasm, myofibril, sarcomere . Cytoplasm, cytoskeleton . Colocalizes with actin filaments in sarcomeres. .
Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603).
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