skeletal system development, ossification, blood vessel development, response to hypoxia, vasculature development,blood vessel maturation, intramembranous ossification, proteolysis, body morphogenesis, developmental maturation,collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process, skeletal system morphogenesis, head development, head morphogenesis, face development, face morphogenesis, trabecula formation, bone trabecula formation, bone development, response to oxygen levels,
[Isoform 1]: Secreted, extracellular space, extracellular matrix . Membrane. Nucleus. Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes.; [Isoform 2]: Cytoplasm. Mitochondrion.
Produced by normal skin fibroblasts. PEX is expressed in a number of tumors including gliomas, breast and prostate.
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