Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins . Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' . Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle .
Cytoplasm . Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Copurifies with ribosomes. .
Heart, gut, kidney, liver and placenta.