Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
下载说明书
