RNA-binding protein involved in translationally coupled mRNA turnover . Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain . Required for efficient formation of stress granules . ; (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA.
Cytoplasm. Cytoplasm, Stress granule . Cytoplasm, P-body .