[Isoform 1]: Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.
Cytoplasm .; [Isoform 1]: Nucleus . Nucleus, nucleolus .; [Isoform 2]: Cytoplasm, cytosol . Cytoplasmic vesicle, clathrin-coated vesicle . Recycling endosome .
[Isoform 1]: Expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. ; [Isoform 2]: Detected at much lower levels in kidney, liver, brain and testis and not detected in heart or skeletal muscle.