Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein . Golgi apparatus, cis-Golgi network membrane ; Single-pass type I membrane protein . Golgi apparatus, Golgi stack membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, COPI-coated vesicle membrane ; Single-pass type I membrane protein . Probably cycles between compartments of the early secretatory pathway. .