Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group in an ATP hydrolysis-dependent manner . May be involved in maintaining the translation efficiency of at least some genes through preventing degradation of their mRNAs . Prefers RNA molecules that are adenosine-rich close to 3'-end . In addition, may inhibit cell proliferation and cell cycle progression through ubiquitination of beta-catenin/CTNNB1 .
Cytoplasm . Nucleus .
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