Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker.
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Strongly expressed in heart, skeletal muscle, brain, prostate, thyroid and trachea.
下载说明书
