Accessory component of the DNA polymerase epsilon complex . Participates in DNA repair and in chromosomal DNA replication (By similarity). Forms a complex with CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 . Does not enhance nucleosome sliding activity of the ACF-5 ISWI chromatin remodeling complex .
Nucleus .
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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