Plays an essential role in neuronal cell migration.
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localized specifically to the pericentriolar region. .
Isoform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL) patients.
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