Part of a kinesin motor-adapter complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development.
[Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Colocalizes with syntaxin vesicles along microtubules in neuronal processes.; [Isoform 3]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 4]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 5]: Golgi apparatus membrane; Single-pass membrane protein.
Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine.
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