Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase . Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme .
Mitochondrion inner membrane ; Multi-pass membrane protein .
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