Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
Cytoplasm, cell cortex . Cell projection, dendritic spine . Remains associated with dendritic spines even after glutamate stimulation. .
Highest expression in brain. Also expressed in kidney, pancreas, lung, heart, liver, skeletal muscle and placenta.
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