Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function . May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity .
Nucleus . Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion matrix . Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. .
Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate.
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