Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
Cytoplasm, myofibril, sarcomere . Cytoplasm, cytoskeleton . Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines. .
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