Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets . In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 .
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
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