mitotic sister chromatid segregation, M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, sister chromatid segregation, DNA packaging, cell cycle, chromosome segregation, mitosis, mitotic chromosome condensation, cell cycle process, cell cycle phase, chromosome condensation, organelle fission, chromosome organization,
Nucleus . Nucleus matrix . Nucleus, nucleolus . Cytoplasm . Associated with the nuclear matrix in interphase and redistributes mostly to chromatin at mitosis. However, mitotic chromatin localization has been questioned. Upon nuclear reassembly at the end of mitosis, is sequestered into the daughter nuclei where it re-acquires an interphase distribution. Exhibits partial localization to the nucleolus in interphase, where it colocalizes with UBTF/UBF, suggesting localization to the fibrillary center and/or to the dense fibrillary component. Colocalizes with GJA1 at the nuclear membrane specifically during cell cycle G1/S phase. .
Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells.
下载说明书
