Stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport . Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers .
Nucleus . Cytoplasm . Detected in the nucleus and cell soma of various neuronal types. .