Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism . Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption .
Apical cell membrane ; Multi-pass membrane protein . Cell membrane .; [Isoform 1]: Cell membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein. Cytoplasm .; [Isoform 2]: Cytoplasm .
Predominantly expressed in testis. Highly expressed in small intestine and prostate.
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