Important for proper ciliary and flagellar beating. May act in cooperation with CFAP45 and axonemal dynein subunit DNAH11 . May play a role in cell growth and/or survival .
Cytoplasm . Cell projection, cilium, flagellum . Cytoplasm, cytoskeleton, cilium axoneme . Located in the proximal region of respiratory cilia. .
Expressed in respiratory cells and sperm (at protein level) (PubMed:33139725). Highly expressed in testis (PubMed:15967112). Up-regulated in hepatocellular carcinoma (HCC) (PubMed:15967112).