Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
[Isoform 1]: Endoplasmic reticulum.; Secreted, extracellular space, extracellular matrix . Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG). .
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