Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, myofibril, sarcomere, A band . Cytoplasm, perinuclear region . Cytoplasm, cytosol . Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage. .
Expressed in eye lens tissues. Expressed in muscle (at protein level) (PubMed:33217308).
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