DNA metabolic process, DNA replication, chromatin organization, transcription, regulation of transcription, DNA-dependent, protein amino acid acetylation, chromatin modification, covalent chromatin modification, histone modification, histone acetylation, protein amino acid acylation, histone H3 acetylation, histone H4 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, regulation of transcription, regulation of RNA metabolic process, chromosome organization,
Nucleus . Chromosome . Chromosome, centromere . Cytoplasm, cytosol . Associates with replication origins specifically during the G1 phase of the cell cycle (PubMed:18832067, PubMed:20129055). Localizes to transcription start sites (PubMed:21753189, PubMed:24065767). Localizes to ultraviolet-induced DNA damage sites following phosphorylation by ATR (PubMed:28719581). Localizes to centromeres in G1 phase (PubMed:27270040). .
Ubiquitously expressed, with highest levels in testis.
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