Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning . Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM . Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM .
Nucleus . Nucleus, nucleolus . Mainly found in the granular component of the nucleolus. .
Ubiquitous.
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